The PW columns, with a spherical packing of porous hydrophilic methacrylate, are the most suitable for molecular exclusion of water soluble synthetic polymers, as they have a more linear calibration curve, a wider range of application and a lower absorption than the SW type columns.
They also demonstrate an excellent mechanical and chemical stability, enabling operation within a pH range of 2 to 12, and can be used with upto 50% of organic solvent as eluant.