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Affinity Chromatography

Dynamic binding capacity (DBC) values for AFC materials vary with the ligand and are typically on the low side. However because most of the capacity is used for the target, with feedstock impurities remaining unbound, AFC resins are typically used for the Capture and Intermediate purification steps of a manufacturing process.

Protein A resins are the most frequently used affinity resins in biomanufacturing. Protein A specifically adsorbs immunoglobulin G and today Protein A chromatography is the standard technique for capturing recombinant monoclonal antibodies.

TOYOPEARL AF-Chelate-650M
TOYOPEARL AF-Red-650ML
TOYOPEARL AF-Amino-650M
TOYOPEARL AF-Carboxy-650M
TOYOPEARL AF-Formyl-650M
TOYOPEARL AF-Tresyl-650M
TOYOPEARL AF-Epoxy-650M

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