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ROMIL Ion-Pair Reagents

Many ionic and highly polar compounds cannot be effectively reversed-phase separated without the use of reagents that form an "ionic pair" with the sample.
Ionic pair reagents improve the peak symmetry of ionic compounds. The efficiency and symmetry of peaks in the separation of basic compounds can be significantly improved by the addition to the mobile phase of the sodium salt of an alkyl sulfonate or alkylsulfate.
The anionic part of these "ionic pair" reagents is associated with the base nullifying its positive charge. The ionic pair also exhibits an increase in hydrophobicity due to the incorporation of the n-alkyl chain. For acid samples, the same effect is achieved by the use of alkylammonium halides.

Specifications
Applications
ROMIL Ion-Pair Reagents

The Purest Reagents for Separation Optimisation in HPLC

Although reversed phase HPLC is one of the most important techniques in chromatography, by itself it is limited to separations of non-ionic (neutral) and non-polar compounds.

Polar or ionic substances tend to separate badly on reversed phase systems. So, bearing in mind that many compounds of biological interest are either ionic or highly polar, what can the HPLC analyst do to improve such separations? Either give up or reach for ROMIL-SpR™ Super Purity Reagents. The addition to the mobile phase of one of these high purity substances, as a counter-ion of opposite charge, enables the sample species to form a neutral 'ion pair' that will now readily interact with the reversed phase packing and thereby permit a clean separation.

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showing 20 of 54 products
Reagent
Acetic Acid (1)
Ammonium Acetate (1)
Ammonium Formate (2)
Butane-1-sulphonic Acid sodium salt (2)
Decane-1-sulphonic Acid sodium salt (2)
Dioctyl Sulphosuccinate sodium salt (2)
Dodecane-1-sulphonic Acid sodium salt (2)
Dodecyltrimethylammonium Bromide (1)
Formic Acid (1)
Heptafluorobutyric Acid (1)
Heptane-1-sulphonic Acid sodium salt (3)
Hexadecyltrimethylammonium Bromide (1)
Hexane-1-sulphonic Acid sodium salt (2)
Methanesulphonic Acid sodium salt (2)
Nonane-1-sulphonic Acid sodium salt (2)
Octane-1-sulphonic Acid sodium salt (4)
Pentane-1-sulphonic Acid sodium salt (3)
Potassium di-Hydrogen Phosphate (2)
Sodium Dodecyl Sulphate (3)
Tetrabutylammonium Bromide (1)
Tetrabutylammonium Hydroxide (2)
Tetrabutylammonium Phosphate (4)
Tetraethylammonium Bromide (1)
Tetraethylammonium Hydrogen Sulphate (1)
Tetramethylammonium Hydrogen Sulphate (3)
Triethylamine (2)
Trifluoroacetic Acid (1)
Tri-n-butylamine (1)
Size
100g (14)
100ml (4)
1KG (3)
1LT (1)
250ml (1)
25g (17)
25ml (1)
500g (3)
500ml (3)
5g (6)
Reference RM-H763P
Description TRIETILAMINA SpS 500 ml
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Reference RM-H763S
Description TRIETILAMINA SpS 100 ml
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Reference RM-HA016M
Description Acetic Acid SpR 1LT
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Reference RM-HA353P
Description Formic Acid SpR, 500ml
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Reference RM-HA353S
Description Formic Acid SpR 100ml
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Reference RM-HA853P
Description Trifluoroacetic Acid SpR 500ml
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Reference RM-HR079P
Description Ammonium Acetate SpR 500g no adr
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Reference RM-HR305P
Description Ammonium Formate SpR 500g no adr
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Reference RM-HR305S
Description Ammonium Formate SpR, 100g no adr
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Reference RM-HR739P
Description Potassium di-Hydrogen Phosphat e SpR, 500g
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Reference RM-HR739S
Description Potassium di-Hydrogen Phosphat e SpR, 100g
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Reference RM-IP201S
Description ACIDO METANOSULFONICO, SAL SOD ICA SpR 100g
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Reference RM-IP201V
Description ACIDO METANOSULFONICO, SAL SOD ICA SpR 25g
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Reference RM-IP204S
Description ACIDO BUTAN-1-SULFONICO SpR SA L SODICA 100g
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Reference RM-IP204V
Description ACIDO BUTAN-1-SULFONICO SpR SA L SODICA 25g
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Reference RM-IP205M
Description ACIDO PENTAN-1-SULFONICO SpR S AL SODICA 1KG
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Reference RM-IP205S
Description ACIDO PENTAN-1-SULFONICO SpR S AL SODICA 100g
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Reference RM-IP205V
Description ACIDO PENTAN-1-SULFONICO SpR  SAL SODICA 25g
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Reference RM-IP206S
Description ACIDO HEXAN-1-SULFONICO SpR SA L SODICA 100g
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Reference RM-IP206V
Description ACIDO HEXAN-1-SULFONICO SpR SA L SODICA 25g
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showing 20 of 54 products