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TOYOPEARL Group Specific Affinity Resins

TOYOPEARL affinity resins are composed of hydrophilic, dimensionally stable base resins that exhibit excellent pressure-flow characteristics. These resins use the TOYOPEARL HW-65 SEC resin as a base bead.

TOYOPEARL affinity resins are functionalized with chemically active groups or group-specific ligands. Resins with activated functional groups are ready to directly couple a protein or other ligand. Resins with reactive groups require carbodiimide coupling or reductive amination to achieve a stable covalent linkage. 

 

TOYOPEARL Group Specific Affinity Resins are functionalized with ligands that bind specific functional groups on your target of interest. 

TOYOPEARL AF-Chelate-650M
TOYOPEARL AF-Red-650ML
TOYOPEARL AF-Heparin HC-650M

TOYOPEARL AF-Chelate-650M resin carries a chelating ligand, iminodiacetic acid (IDA), that can form stable chelate complexes with selected metal ions such as Cu2+, Ni2+, Zn2+ and Co2+. The resultant resin can be used for immobilized metal affinity chromatography (IMAC). It binds to histidine rich/histidine tagged proteins and to cysteine containing proteins.

 

AFC_Chelate_structure.jpg

TOYOPEARL AF-Red-650ML is functionalized with Procion Red HE-3B (also known as Reactive Red 120). This resin is useful for the purification of nucleotide-dependent enzymes, lipoproteins, plasminogen, peptides, hormones and cytotoxins.

 

AFC_Red_structure.jpg

TOYOPEARL AF-Heparin HC-650M is a high capacity, affinity adsorbent with excellent chemical stability. The heparin ligand is a linear and highly sulfated glycosaminoglycan which has anti-coagulant properties.

Due to its polyanionic nature, heparin interacts with a wide range of biomolecules including plasma components, lipoprotein lipase, collagenase, and DNA polymerase. Immobilized heparin is widely used as an adsorbent in affinity chromatography for the purification of biological substances.

 

AFC_Heparin_structure.jpg

Choose your product
showing 3 of 3 products
Technology
Affinity (3)
Support
HW (3)
Function
AF-HeparinHC (3)
Pore Size
1000 Å (3)
Particle Size
65 µm (3)
Reference TH-20030
Description Toyopearl AF-HeparinHC-650M, 6 5 µm, 1.000 Å 10ml        
Price 181,00€
Quantity
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Reference TH-20031
Description AF-HeparinHC-650M, 65 µm,  1.000 Å  polymer   100 ml
Price 1.054,00€
Quantity
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Reference TH-20032
Description Toyopearl AF-HeparinHC-650M, 6 5 µm, 1.000 Å 1L      
Price 9.647,00€
Quantity
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showing 3 of 3 products