Liquid Chromatography-Mass Spectrometry
Liquid chromatography paired with mass spectrometry (LC-MS) is an extremely sensitive technique and therefore requires solvents of the ultimate purity. ROMIL‑UpS™ ultra lc products are purified to meet the stringent criteria demanded by analysts. They feature:
- Suitability testing for LC-MS
- Extremely low levels of ionic impurities
- Minimal baseline drift
ROMIL‑UpS™ ultra-lc solvents are compatible with ESI/APCI ionisation methods in both positive and negative modes. Additionally, their low ionic background resulting in low ion suppression make ROMIL‑UpS™ solvents the ultimate choice.
Liquid Chromatography-Inductively Coupled Plasma-Mass SpectrometryThe coupling of liquid chromatography with ICP-MS (LC-ICP-MS) offers many advantages for speciation analysis. With background ionic impurities controlled to low ppb levels, ROMIL‑UpS™ ultra lc solvents are eminently suited to this triple hyphenated technique.
Ultra High Performance Liquid ChromatographyIn contrast to traditional HPLC, Ultra High Performance Liquid Chromatography (UHPLC) combines sub 2 micron particles in smaller diameter columns of shorter length on higher pressure instrumentation enabling enhanced resolution and efficiency of chromatographic separation. Although the resulting lower flow rates and shorter run times require less solvent, the purity demands on the solvent are increased. ROMIL‑UpS™ ultra lc solvents have the performance to more than play their part.
Gas Chromatography-Mass SpectrometryThe Gas Chromatography-Mass Spectrometry (GC-MS) technique requires volatile organic solvents such as dichloromethane, hexane, methanol, acetonitrile and ethyl acetate. ROMIL‑UpS™ ultra gc versions of these solvents are carefully distilled in glass to produce the ultimate purity and are use tested for GC-MS, GC-ECD and GC-FID.
Gas Chromatography-Inductively Coupled Plasma-Mass SpectrometryCoupling of gas chromatography with ICP-MS permits the simultaneous determination of many elements. The hyphenated technique is particularly suited to the speciation of a number of metals, including lead, mercury and zinc. By virtue of the purification technique ROMIL‑UpS™ ultra gc solvents feature metallic levels in the low ppb range which makes them ideal for use in GC-ICP-MS.
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